2019 Year 12 IB Extended Essays

Appendix

Raw Data

Table 1: Average signal of heart muscle cells for each transcription factor and comparison to other tissue types (Human body index) Transcription factor Other tissue types that have similar or higher signal value

Average signal of heart muscle cells

90% of Average signal of heart muscle cells

Baf60c

432.01

388.81

Brain Quadriceps

Gata4

145.43

130.89

Ovary Skin

Duodenum Pancreas

Hand2

26.91

24.22

Ovary Oocyte Brain Stomach

Colon Cecum Saphenus vein Lymph nodes Endometrium

Hopx

11.5

10.35

Brain Spinal cord Trigmenial Ganglion Skin Breast Bronchus

Colon cecum Thyroid gland Prostate gland Deltoid muscle Tongue Synovial membrane Bone marrow T cells and B cells Lymph nodes Spleen Uterus and placenta Saphenous vein Coronary artery Joint tissue synovium Endometrium

Oral mucosa Salivary gland

Stomach Jejunum

Hrt2 (Hey2)

207.44

186.70

Brain Spinal cord Dorsal root/ trigeminal ganglia Low expression in heart

Isl1

16.96 107.97

15.26 97.17

Mef2c

Brain Jejunum Colon cecum Adipose tissue Saphenous vein Coronary artery Skeletal muscle

Tongue Skeletal muscle Tonsil Spleen White blood cells Uterus Myometrium

Mesp1

63.56

57.20

Oocyte

Jejunum

16